Article
Clinical follow-up of two Brazilian subjects with glucokinase-MODY (MODY2) with description of a novel mutation.
Arquivos brasileiros de endocrinologia e metabologia - 1 Nov 2012
DellaManna Thais, Silva Magnus R da, Chacra Antonio Roberto, Kunii Ilda S, Rolim Ana Luiza, Furuzawa Gilberto, Maciel Rui Monteiro de Barros, Reis André Fernandes
Abstract excerpt
Mutations in the glucokinase gene (GCK) account for many cases of monogenic diabetes featuring maturity-onset diabetes of the young type 2 (MODY2). The clinical pattern of this form of hyperglycemia is rather stable, with a slight elevation in blood glucose, which is usually not progressive. Patients rarely require pharmacological interventions and microvascular complications related to diabetes are unusual. We...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.