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Article

Lack of association between IL27 gene variants and type 1 diabetes susceptibility.

Cytokine - 1 Feb 2013

Santos Aritania S, Melo Maria E, Crisóstomo Lindiane G, Fukui Rosa T, Matioli Sérgio R, Silva Maria Elizabeth R

Abstract excerpt

BACKGROUND: Recently, a new subpopulation of T cells, the Th17 subset, has been implicated in autoimmune diseases. Its development is influenced by IL-27, expressed in macrophages or dendritic cells. IL-27 blockage delays the onset of diabetes in non obese diabetes mouse, but its role in type 1 diabetes (T1D) in human has not been reported yet. The aim of this study was identify variants in the entire coding...

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Identifiers

PMID: 23294976
DOI: 10.1016/j.cyto.2012.12.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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