Article
The influence of a TNF gene polymorphism on the severity of rheumatoid arthritis in the Brazilian Amazon.
Cytokine - 1 Feb 2013
Boechat Antonio Luiz, Boechat Narjara de Oliveira, Ogusku Mauricio Morishi, Alencar Mariana Raposo, Abensur Themis da Costa, Cardoso Neto José, Amorim Leilian de Souza, de Oliveira Lívia Moura, Sadahiro Aya, Dos-Santos Maria Cristina
Abstract excerpt
PURPOSE: The aim of this study was to investigate the influence of the TNF -308 G/A polymorphism in the promoter region of the tumor necrosis factor-α gene on the susceptibility and severity of rheumatoid arthritis (RA) in individuals from the Brazilian Amazon. METHODS: A total of 323 individuals-192 healthy controls without arthritis and 131 individuals suffering from arthritis-were genotyped for this...
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