Article
HLA-AR, an inactivated antigen-presenting locus related to HLA-A. Implications for the evolution of the MHC.
Journal of immunology (Baltimore, Md. : 1950) - 1 May 1990
Zemmour J, Koller B H, Ennis P D, Geraghty D E, Lawlor D A, Orr H T, Parham P
Abstract excerpt
The MHC contains many class I genes other than those known to present peptides to T lymphocytes. These additional class I genes vary between species and their functions are unknown. Genes involved in Ag presentation, HLA-A,B,C in humans, are highly diverse whereas other class I genes are of much...
Topics
- Alleles
- Amino Acid Sequence
- Antigen-Presenting Cells
- Base Sequence
- Biological Evolution
- Cloning, Molecular
- Histocompatibility Antigens Class I
- Humans
- Introns
- Major Histocompatibility Complex
- Membrane Glycoproteins
- Molecular Sequence Data
- Multigene Family
- Protein Sorting Signals