Article
The ROK family regulator Rok7B7 pleiotropically affects xylose utilization, carbon catabolite repression, and antibiotic production in streptomyces coelicolor.
Journal of bacteriology - 1 Mar 2013
Świątek Magdalena A, Gubbens Jacob, Bucca Giselda, Song Eunjung, Yang Yung-Hun, Laing Emma, Kim Byung-Gee, Smith Colin P, van Wezel Gilles P
Abstract excerpt
Members of the ROK family of proteins are mostly transcriptional regulators and kinases that generally relate to the control of primary metabolism, whereby its member glucose kinase acts as the central control protein in carbon control in Streptomyces. Here, we show that deletion of SCO6008 (rok7B7) strongly affects carbon catabolite repression (CCR), growth, and antibiotic production in Streptomyces coelicolor....
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