Article
Quantitative Proteome and Phosphoproteome Analyses of Streptomyces coelicolor Reveal Proteins and Phosphoproteins Modulating Differentiation and Secondary Metabolism.
Molecular & cellular proteomics : MCP - 1 Aug 2018
Rioseras Beatriz, Shliaha Pavel V, Gorshkov Vladimir, Yagüe Paula, López-García María T, Gonzalez-Quiñonez Nathaly, Kovalchuk Sergey, Rogowska-Wrzesinska Adelina, Jensen Ole N, Manteca Angel
Abstract excerpt
Streptomycetes are multicellular bacteria with complex developmental cycles. They are of biotechnological importance as they produce most bioactive compounds used in biomedicine, e.g. antibiotic, antitumoral and immunosupressor compounds. Streptomyces genomes encode many Ser/Thr/Tyr kinases, making this genus an outstanding model for the study of bacterial protein phosphorylation events. We used mass spectrometry...
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