Article
Possible involvement of the sco2127 gene product in glucose repression of actinorhodin production in Streptomyces coelicolor.
Canadian journal of microbiology - 1 Oct 2012
Forero Angela, Sánchez Mauricio, Chávez Adán, Ruiz Beatriz, Rodríguez-Sanoja Romina, Servín-González Luis, Sánchez Sergio
Abstract excerpt
Streptomyces coelicolor mutants resistant to 2-deoxyglucose are insensitive to carbon catabolite repression (CCR). Total reversion to CCR sensitivity is observed by mutant complementation with a DNA region harboring both glucose kinase glkA gene and the sco2127 gene. The sco2127 is located upstream of glkA and encodes a putative protein of 20.1 kDa. In S. coelicolor, actinorhodin production is subject to glucose...
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