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Pleiotropic effect of the SCO2127 gene on the glucose uptake, glucose kinase activity and carbon catabolite repression in Streptomyces peucetius var. caesius.

Microbiology (Reading, England) - 1 May 2005

Guzmán Silvia, Carmona Alonso, Escalante Laura, Imriskova Iveta, López Ruth, Rodríguez-Sanoja Romina, Ruiz Beatriz, Servín-González Luis, Sánchez Sergio, Langley Elizabeth

Abstract excerpt

SCO2127 and SCO2126 (glkA) are adjacent regions located in Streptomyces coelicolor DNA. glkA encodes glucose kinase (Glk), which has been implicated in carbon catabolite repression (CCR) in the genus Streptomyces. In this work, the glkA and SCO2127 genes from S. coelicolor were used, either individually or together, to transform three mutants of Streptomyces peucetius var. caesius resistant to CCR. These mutants...

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PMID: 15870479
DOI: 10.1099/mic.0.27557-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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