Article
The role of p21 3'UTR gene polymorphism in the risk of prostate cancer: a pilot study.
Molecular medicine reports - 1 Mar 2013
Sivoňová Monika Kmetová, Vilčková Marta, Jurečeková Jana, Hatok Jozef, Dobrota Dušan, Dušenka Róbert, Kliment Ján
Abstract excerpt
The cell cycle regulator p21 plays an important role in regulating critical cell activities including cell cycle control, DNA repair and apoptosis. Consequently, it may affect the efficacy of the response to DNA damage and tumor development. The aim of our study was to evaluate the frequencies of the p21 C70T polymorphism, the association between this genetic variant and smoking status, and the serum...
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