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Article

Regulation of epithelial cell turnover and macrophage phenotype by epithelial cell-derived transforming growth factor beta1 in the mammary gland.

Cytokine - 1 Feb 2013

Sun Xuan, Robertson Sarah A, Ingman Wendy V

Abstract excerpt

Transforming growth factor beta1 (TGFB1) is a multi-functional cytokine that regulates cell proliferation, apoptosis and immune system responses. In the breast, the mammary epithelium is the primary source of TGFB1 and increased expression is associated with increased breast cancer risk. This study was conducted to investigate the roles of epithelial cell-derived TGFB1 in regulation of epithelial cell activity...

Read the complete abstract on PubMed

Topics

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Share to Epithelial Cells
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Mammary Glands, Animal

Share to Mice, SCID

Share to Nitric Oxide Synthase Type II

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Source

Identifiers

PMID: 23290315
DOI: 10.1016/j.cyto.2012.12.002

Genes

TGFB1
CCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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