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Article

Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line

20 Aug 2003

Abstract excerpt

BACKGROUND: Transforming growth factor beta (TGF-beta) plays an essential role in a wide array of cellular processes. The most well studied TGF-beta response in normal epithelial cells is growth inhibition. In some cell types, TGF-beta induces an epithelial to mesenchymal transition (EMT). NMuMG is a nontransformed mouse mammary gland epithelial cell line that exhibits both a growth inhibitory response and an EMT...

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PMID: 14580254
DOI: 10.1186/bcr640

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