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Article

The impact of GPX1 on the association of groundwater selenium and depression: a Project FRONTIER study.

BMC psychiatry - 4 Jan 2013

Johnson Leigh A, Phillips Jack A, Mauer Cortney, Edwards Melissa, Balldin Valerie Hobson, Hall James R, Barber Robert, Conger Tori L, Ho Eric J, O'Bryant Sid E

Abstract excerpt

BACKGROUND: Prior animal model and human-based studies have linked selenium concentrations to decreased risk for depression; however, this work has not focused on household groundwater levels or specific depressive symptoms. The current study evaluated the link between groundwater selenium levels and depression. We also sought to determine if a functional polymorphism in the glutathione peroxidase 1 (GPX1) gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23289525
DOI: 10.1186/1471-244X-13-7
PMCID: PMC3566946

Genes

GPX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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