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Article

The transcription factor ETS-1: its role in tumour development and strategies for its inhibition.

Mini reviews in medicinal chemistry - 1 Oct 2008

Hahne Jens Claus, Okuducu Ali Fuat, Sahin Aygün, Fafeur Veronique, Kiriakidis Serafim, Wernert Nicolas

Abstract excerpt

Transcription factors are an important group of proteins. Changes in expression or activity of transcription factors result in diverse and manifold effects on the whole transcriptome of the cell. Therefore transcription factors are of special interest in physiological as well as pathological processes particularly tumour development and progression. In this review we focus on Ets-1, the prototype of the ETS...

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Identifiers

PMID: 18855726
DOI: 10.2174/138955708785909934

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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