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Article

Lectin-based Immunoassay for Aberrant IgG Glycosylation as the Biomarker for Crohnʼs Disease

20 Dec 2012

Abstract excerpt

BACKGROUND: Easily measured and clinically useful biomarkers for inflammatory bowel disease (IBD) are required to advance patient care. We previously reported that the agalactosyl fraction among fucosylated IgG oligosaccharides is increased in IBD, especially Crohn's disease (CD). The present study aimed to establish a simple detection system for aberrant glycosylated IgG based on lectin-oligosaccharide...

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PMID: 23287897
DOI: 10.1097/mib.0b013e318280eade

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