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Article

Distribution of IgG galactosylation as a promising biomarker for cancer screening in multiple cancer types

1 Jul 2016

Abstract excerpt

Cancer is prevalent worldwide. Currently, most routinely used non-invasive serological cancer biomarkers, including carcino-embryonic antigen (CEA), prostate-specific antigen (PSA), α-fetoprotein (AFP), CA125, CA15-3, and CA19-9, suffer from low specificity and/or low sensitivity 1 . Improvements in timely and effective diagnosis of cancer are urgently needed. Most serum proteins are glycosylated, and...

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PMID: 27364686
DOI: 10.1038/cr.2016.83

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