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Serum IgG N‐glycans enable early detection and early relapse prediction of colorectal cancer

19 Sept 2022

Abstract excerpt

Colorectal cancer (CRC) develops mainly from colorectal advanced adenomas (AA), which are considered precancerous lesions. Novel early diagnostic biomarkers are urgently needed to distinguish CRC and AA from healthy control (HC). Alternative glycosylation of serum IgG has been shown to be closely associated with CRC. We aimed to explore the potential of IgG N-glycan as biomarkers in the early differential...

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PMID: 36121650
DOI: 10.1002/ijc.34298

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