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Article

OBFC2A/RARA: a novel fusion gene in variant acute promyelocytic leukemia

4 Jan 2013

Abstract excerpt

Acute promyelocytic leukemia is characterized by the rearrangement of the retinoic acid receptor α (RARA) gene and its fusion with other genes. We report a novel case of variant acute promyelocytic leukemia with the karyotype der (2)t(2;17)(q32;q21). Array comparative genomic hybridization revealed distinct chromosome breakpoints within the RARA and oligonucleotide/oligosaccharide-binding fold containing 2A...

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Identifiers

PMID: 23287866
DOI: 10.1182/blood-2012-04-423129

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