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Article

A novel NUP98/RARG gene fusion in acute myeloid leukemia resembling acute promyelocytic leukemia

9 Oct 2010

Abstract excerpt

Chromosomal translocations in hematological malignancies often result in novel fusion chimeric genes. We report a case of acute myeloid leukemia with a clonal translocation t(11;12)(p15;q13) displaying morphologic and immunophenotypic features resembling the classical hypergranular subtype of acute promyelocytic leukemia. The gene fused to NUP98 (nucleoporin 98) was detected by comparative genomic hybridization...

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PMID: 20935257
DOI: 10.1182/blood-2010-06-291658

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