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Article

The role of the delta-lysin gene (hld) in the regulation of virulence genes by the accessory gene regulator (agr) in Staphylococcus aureus.

The EMBO journal - 1 May 1990

Janzon L, Arvidson S

Abstract excerpt

The synthesis of at least 14 extracellular toxins and enzymes in Staphylococcus aureus is regulated by a set of trans-acting elements from the agr (accessory gene regulator) locus. We have shown that the delta-lysin gene (hld) that is transcribed from a promoter immediately upstream of the agr locus, and which is positively controlled by agr, is part of this regulatory system. Deletion replacement mutagenesis of...

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Identifiers

PMID: 2328718
DOI: 10.1002/j.1460-2075.1990.tb08254.x
PMCID: PMC551825

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Source receipt: pubmed, retrieved 7 Sept 2026.

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