Article
Regulation of exoprotein expression in Staphylococcus aureus by a locus (sar) distinct from agr.
Proceedings of the National Academy of Sciences of the United States of America - 15 Jul 1992
Cheung A L, Koomey J M, Butler C A, Projan S J, Fischetti V A
Abstract excerpt
A single insertion of transposon Tn917LTV1 into the chromosome of a Staphylococcus aureus clinical isolate, strain DB, resulted in a pleiotropic effect on the expression of a number of extracellular and cell-wall-associated proteins. Detailed comparison of phenotypes associated with the mutant, 11D2, and the parent, DB, indicated that the chromosomal locus inactivated as a result of transposon mutagenesis differs...
Topics
- Bacterial Proteins
- DNA Transposable Elements
- Extracellular Space
- Genes, Bacterial
- Mutagenesis, Insertional
- Phenotype
- Plasmids
- Restriction Mapping
- Staphylococcus aureus
- Transduction, Genetic