Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of exoprotein expression in Staphylococcus aureus by a locus (sar) distinct from agr.

Proceedings of the National Academy of Sciences of the United States of America - 15 Jul 1992

Cheung A L, Koomey J M, Butler C A, Projan S J, Fischetti V A

Abstract excerpt

A single insertion of transposon Tn917LTV1 into the chromosome of a Staphylococcus aureus clinical isolate, strain DB, resulted in a pleiotropic effect on the expression of a number of extracellular and cell-wall-associated proteins. Detailed comparison of phenotypes associated with the mutant, 11D2, and the parent, DB, indicated that the chromosomal locus inactivated as a result of transposon mutagenesis differs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to DNA Transposable Elements

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Bacterial

Share to Mutagenesis, Insertional

Share to Phenotype

Share to Plasmids

Share to Restriction Mapping

Share to Staphylococcus aureus

Source

Open in PubMed Open full text

Identifiers

PMID: 1321441
DOI: 10.1073/pnas.89.14.6462
PMCID: PMC49521

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of exoprotein expression in Staphylococcus aureus by a locus (sar) distinct from agr.PMID 1321441Read ↗

The role of the delta-lysin gene (hld) in the regulation of virulence genes by the accessory gene regulator (agr) in Staphylococcus aureus.Semantic proximity Read ↗

Therapeutic Targeting of the Staphylococcus aureus Accessory Gene Regulator (agr) SystemSemantic proximity Read ↗

Strain-Dependent Differences in the Regulatory Roles of sarA and agr in Staphylococcus aureusSemantic proximity Read ↗

Role of SarA in virulence determinant production and environmental signal transduction in Staphylococcus aureus.Semantic proximity Read ↗

The extracellular protein regulator (xpr) affects exoprotein and agr mRNA levels in Staphylococcus aureus.Semantic proximity Read ↗

Role of the Accessory Gene Regulator <i>agr</i> in Community-Associated Methicillin-Resistant Staphylococcus aureus PathogenesisSemantic proximity Read ↗

sarA negatively regulates S taphylococcus epidermidis biofilm formation by modulating expression of 1 MDa extracellular matrix binding protein and autolysis‐dependent release of eDNASemantic proximity Read ↗

Quorum sensing-mediated regulation of staphylococcal virulence and antibiotic resistance.Semantic proximity Read ↗

Transcriptional profiling of a Staphylococcus aureus clinical isolate and its isogenic agr and sarA mutants reveals global differences in comparison to the laboratory strain RN6390Semantic proximity Read ↗

Characterization of theStaphylococcus epidermidisAccessory‐Gene Regulator Response: Quorum‐Sensing Regulation of Resistance to Human Innate Host DefenseSemantic proximity Read ↗

Quorum-sensing regulation in staphylococci—an overviewSemantic proximity Read ↗

Staphylococcus epidermidis agr Quorum-Sensing System: Signal Identification, Cross Talk, and Importance in ColonizationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.