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Article

A new system for parallel drug screening against multiple-resistant HIV mutants based on lentiviral self-inactivating (SIN) vectors and multi-colour analyses

3 Jan 2013

Abstract excerpt

BACKGROUND: Despite progress in the development of combined antiretroviral therapies (cART), HIV infection remains a significant challenge for human health. Current problems of cART include multi-drug-resistant virus variants, long-term toxicity and enormous treatment costs. Therefore, the identification of novel effective drugs is urgently needed. METHODS: We developed a straightforward screening approach for...

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Share to Advanced biosensing and bioanalysis techniques
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23286882
DOI: 10.1186/1742-6405-10-1

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