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Article

A population-based study of hereditary non-polyposis colorectal cancer: evidence of pathologic and genetic heterogeneity.

Clinical genetics - 1 Dec 2013

Warden G, Harnett D, Green J, Wish T, Woods M O, Green R, Dicks E, Rahman P, Zhai G, Parfrey P

Abstract excerpt

Hereditary non-polyposis colorectal cancer (HNPCC) may be the result of Lynch syndrome (LS) caused by mutations in mismatch repair (MMR) genes, a syndrome of unknown etiology called familial colorectal cancer type-X (FCCTX), or familial serrated neoplasia associated with the colorectal cancer (CRC) somatic BRAF mutation. To determine the cause of HNPCC in the founder population of the island of Newfoundland, we...

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Identifiers

PMID: 23278430
DOI: 10.1111/cge.12080

Genes

BRAF
MSH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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