Article
A large-scale candidate gene analysis of mood disorders: evidence of neurotrophic tyrosine kinase receptor and opioid receptor signaling dysfunction.
Psychiatric genetics - 1 Apr 2013
Deo Anthony J, Huang Yung-yu, Hodgkinson Colin A, Xin Yurong, Oquendo Maria A, Dwork Andrew J, Arango Victoria, Brent David A, Goldman David, Mann J John, Haghighi Fatemeh
Abstract excerpt
BACKGROUND: Despite proven heritability, little is known about the genetic architecture of mood disorders. Although a number of family and case-control studies have examined the genetics of mood disorders, none have carried out joint linkage-association studies and sought to validate the results with gene expression analyses in an independent cohort. METHODS: We present findings from a large candidate gene study...
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