Article
Estrogen metabolism within the lung and its modulation by tobacco smoke.
Carcinogenesis - 1 Apr 2013
Peng Jing, Xu Xia, Mace Brian E, Vanderveer Lisa A, Workman Laura R, Slifker Michael J, Sullivan Patrick M, Veenstra Timothy D, Clapper Margie L
Abstract excerpt
Although estrogen and the enzymes responsible for its metabolism have been detected within the lung, the ability of this tissue to metabolize estrogen has not been demonstrated previously. The goal of this study was to characterize the profile of estrogen metabolites within the murine lung and to determine the effect of tobacco smoke exposure on metabolite levels. Use of liquid chromatography-tandem mass...
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