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COPD-Like Phenotypes in TBC-Treated Mice Can be Effectively Alleviated via Estrogen Supplement.

Environmental science & technology - 1 Oct 2024

Zhang Wenjuan, Wang Yuxin, Wang Ling, Cao Mengxi, Cao Huiming, Song Maoyong, Qian Yun, Wang Thanh, Liang Yong, Jiang Guibin

Abstract excerpt

Tris(2,3-dibromopropyl) isocyanurate (TBC), recognized as an endocrine disruptor, can cause inflammatory injury to the lung tissue of mice. To investigate the specific respiratory effects of TBC, male C57BL/6J mice were administered a daily dose of 20 mg/kg of TBC over 14 days. Postexposure, these mice developed chronic obstructive pulmonary disease (COPD)-like symptoms characterized by inflammatory lung damage...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39166923
DOI: 10.1021/acs.est.4c03187

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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