Article
Factor VII levels, R353Q and -323P0/10 Factor VII variants, and the risk of acute coronary syndrome among Arab-African Tunisians.
Molecular biology reports - 1 May 2013
Ben-Hadj-Khalifa Sonia, Lakhal Basma, Nsiri Brahim, Mahjoub Touhami, Almawi Wassim Y
Abstract excerpt
The importance of the extrinsic haemostatic system, of which factor VII/VIIa (FVII/FVIIa) is a key constituent, in acute coronary syndrome (ACS) is well recognized. The contribution of FVII gene variants R353Q and -323P0/10, and altered FVII plasma levels to the risk of ACS was investigated in a North African Tunisian Arab cohort consisting of 308 ACS cases and 312 age-, gender- and ethnically-matched control...
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