Association Between the G20210A Polymorphism of Prothrombin Gene and Myocardial Infarction in Tunisian Population.

doi:10.1007/s10528-016-9744-y

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Article

Association Between the G20210A Polymorphism of Prothrombin Gene and Myocardial Infarction in Tunisian Population.

Biochemical genetics - 1 Oct 2016

Kallel Amani, Sbaï Mohamed Hedi, Sédiri Yousra, Feki Moncef, Mourali Mohamed Sami, Mechmeche Rachid, Jemaa Riadh, Kaabachi Naziha

Abstract excerpt

The prothrombin is the precursor of the serine protease thrombin, a key enzyme in homeostasis. Prothrombin G20210A polymorphism (rs1799963) was described as a moderate risk factor for venous thrombosis because this mutation is associated with prothrombin elevated levels which may lead to an imbalance between the procoagulant, anticoagulant, and fibrinolytic system. 20210A carriers have an increased risk of...

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PMID: 27306359
DOI: 10.1007/s10528-016-9744-y

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