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Article

23S rRNA mutation A2074C conferring high-level macrolide resistance and fitness cost in Campylobacter jejuni.

Microbial drug resistance (Larchmont, N.Y.) - 1 Dec 2009

Hao Haihong, Dai Menghong, Wang Yulian, Peng Dapeng, Liu Zhenli, Yuan Zonghui

Abstract excerpt

To examine the development of macrolide resistance in Campylobacter jejuni and assess the fitness of the macrolide-resistant mutants, two macrolide-susceptible C. jejuni strains, American Type Culture Collection (ATCC) 33291 and H1, from different geographic areas were exposed to tylosin in vitro. Multiple mutant strains were obtained from the selection. Most of the high-level macrolide-resistant strains derived...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19857128
DOI: 10.1089/mdr.2009.0008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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