Article
23S rRNA gene mutations contributing to macrolide resistance in Campylobacter jejuni and Campylobacter coli.
Foodborne pathogens and disease - 1 Jan 2000
Ladely Scott R, Meinersmann Richard J, Englen Mark D, Fedorka-Cray Paula J, Harrison Mark A
Abstract excerpt
The genetic basis of macrolide resistance in Campylobacter coli (n = 17) and C. jejuni (n = 35) isolates previously subjected to in vivo selective pressure was investigated to determine if the number of copies of 23S rRNA genes with macrolide-associated mutations affects the minimum inhibitory concentration (MIC) of macrolides. Sequence data for domain V of the 23S rRNA gene revealed that two macrolide-resistant...
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