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Article

Identification of a novel G2073A mutation in 23S rRNA in amphenicol-selected mutants of Campylobacter jejuni.

PloS one - 1 Jan 2014

Ma Licai, Shen Zhangqi, Naren Gaowa, Li Hui, Xia Xi, Wu Congming, Shen Jianzhong, Zhang Qijing, Wang Yang

Abstract excerpt

OBJECTIVES: This study was conducted to examine the development and molecular mechanisms of amphenicol resistance in Campylobacter jejuni by using in vitro selection with chloramphenicol and florfenicol. The impact of the resistance development on growth rates was also determined using in vitro culture. METHODS: Chloramphenicol and florfenicol were used as selection agents to perform in vitro stepwise selection....

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Share to Amino Acid Substitution
Share to Campylobacter jejuni

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chloramphenicol

Share to Drug Resistance, Bacterial

Share to Kinetics

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Share to RNA, Ribosomal, 23S

Source

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Identifiers

PMID: 24728007
DOI: 10.1371/journal.pone.0094503
PMCID: PMC3984149

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