Article
Septin-containing barriers control the differential inheritance of cytoplasmic elements.
Cell reports - 31 Jan 2013
Tartakoff Alan Michael, Aylyarov Ilya, Jaiswal Purnima
Abstract excerpt
Fusion of haploid cells of Saccharomyces cerevisiae generates zygotes. We observe that the zygote midzone includes a septin annulus and differentially affects redistribution of supramolecular complexes and organelles. Redistribution across the midzone of supramolecular complexes (polysomes and Sup35p-GFP [PSI+]) is unexpectedly delayed relative to soluble proteins; however, in [psi-] × [PSI+] crosses, all buds...
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