Article
Assembly, molecular organization, and membrane-binding properties of development-specific septins.
The Journal of cell biology - 29 Feb 2016
Garcia Galo, Finnigan Gregory C, Heasley Lydia R, Sterling Sarah M, Aggarwal Adeeti, Pearson Chad G, Nogales Eva, McMurray Michael A, Thorner Jeremy
Abstract excerpt
Septin complexes display remarkable plasticity in subunit composition, yet how a new subunit assembled into higher-order structures confers different functions is not fully understood. Here, this question is addressed in budding yeast, where during meiosis Spr3 and Spr28 replace the mitotic septin subunits Cdc12 and Cdc11 (and Shs1), respectively. In vitro, the sole stable complex that contains both...
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