Article
Comparison of metagenomic samples using sequence signatures.
BMC genomics - 27 Dec 2012
Jiang Bai, Song Kai, Ren Jie, Deng Minghua, Sun Fengzhu, Zhang Xuegong
Abstract excerpt
BACKGROUND: Sequence signatures, as defined by the frequencies of k-tuples (or k-mers, k-grams), have been used extensively to compare genomic sequences of individual organisms, to identify cis-regulatory modules, and to study the evolution of regulatory sequences. Recently many next-generation sequencing (NGS) read data sets of metagenomic samples from a variety of different environments have been generated. The...
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