Article

Longitudinal differential abundance analysis of microbial marker-gene surveys using smoothing splines

2017-01-10

Abstract excerpt

<h4>Background</h4> High-throughput targeted sequencing of the 16S ribosomal RNA marker gene is often used to profile and characterize the taxonomic composition of microbial communities. This type of big high-through sequencing data is rapidly being applied to various infectious diseases like diarrhea. While many studies are limited to single “snapshots” of these communities, there is increasing recognition that...

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Literature Corpus work: d776444a-0e12-581c-89ba-8e4dce8bbd62
DOI: 10.1101/099457

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