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Article

CYP2C19*17 gain-of-function polymorphism is associated with peptic ulcer disease.

Clinical pharmacology and therapeutics - 1 Feb 2013

Musumba C O, Jorgensen A, Sutton L, Van Eker D, Zhang E, O'Hara N, Carr D F, Pritchard D M, Pirmohamed M

Abstract excerpt

Single-nucleotide polymorphisms (SNPs) in the CYP2C gene cluster have been extensively investigated as predisposing factors for nonsteroidal anti-inflammatory drug (NSAID)-induced peptic ulcer disease (PUD) or upper gastrointestinal bleeding (UGIB). However, results have been inconclusive owing to different study designs, limited genotyping strategies, and small sample sizes. We investigated whether eight...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23267857
DOI: 10.1038/clpt.2012.215

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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