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Article

Effect of CYP2C19*17 gene variant on Helicobacter pylori eradication in peptic ulcer patients.

European journal of clinical pharmacology - 1 Oct 2006

Kurzawski Mateusz, Gawrońska-Szklarz Barbara, Wrześniewska Joanna, Siuda Andrzej, Starzyńska Teresa, Droździk Marek

Abstract excerpt

OBJECTIVE: Eradication of Helicobacter pylori is an important treatment strategy in peptic ulcer patients. Current regimens of eradication consist of proton pump inhibitor (PPI) and two antibiotics. The principal enzyme involved in PPIs metabolism is CYP2C19, which exhibits an interindividual variability of activity, mainly due to genetic polymorphism. Two alleles (CYP2C19*2 and CYP2C19*3), responsible for slow...

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Identifiers

PMID: 16912869
DOI: 10.1007/s00228-006-0183-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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