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Article

Incorporating parental information into family-based association tests.

Biostatistics (Oxford, England) - 1 Jul 2013

Yu Zhaoxia, Gillen Daniel, Li Carey F, Demetriou Michael

Abstract excerpt

Assumptions regarding the true underlying genetic model, or mode of inheritance, are necessary when quantifying genetic associations with disease phenotypes. Here we propose new methods to ascertain the underlying genetic model from parental data in family-based association studies. Specifically, for parental mating-type data, we propose a novel statistic to test whether the underlying genetic model is additive,...

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Identifiers

PMID: 23266418
DOI: 10.1093/biostatistics/kxs048
PMCID: PMC3732025

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MGAT5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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