Article
Constructing deletions with defined endpoints in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America - 1 Apr 1990
Cooley L, Thompson D, Spradling A C
Abstract excerpt
Chromosomes bearing small deletions are valuable tools in Drosophila genetics. We have investigated a method for efficiently constructing precise chromosomal deficiencies. Two P transposable elements were positioned within a progenitor strain at the sites of the desired deletion endpoints. Deletions spanning the two transposons were recovered at high frequency when P element transposase was expressed in these...
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