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Article

Immunosenescence-Associated Micrornas in Age and Heart Failure

20 Dec 2012

Abstract excerpt

AIMS: Ageing of the immune system, immunosenescence, is characterized by impaired lymphopoiesis, especially B-lymphocyte maturation, and is a hallmark of chronic heart failure (CHF). MicroRNAs (miRNAs) are non-coding, small RNAs, which post-transcriptionally control gene expression of multiple target genes. The miR-181 family is known to control haematopoietic lineage differentiation. Here, we study the role of...

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PMID: 23258801
DOI: 10.1093/eurjhf/hfs184

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