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Article

Inflammation-associated microRNA changes in circulating exosomes of heart failure patients

1 Dec 2017

Abstract excerpt

OBJECTIVE: MiR-486 and miR-146a are cardiomyocyte-enriched microRNAs that control cell survival and self-regulation of inflammation. These microRNAs are released into circulation and are detected in plasma or in circulating exosomes. Little is known whether heart failure affects their release into circulation, which this study investigated. RESULTS: Total and exosome-specific microRNAs in plasma of 40 heart...

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PMID: 29258606
DOI: 10.1186/s13104-017-3090-y

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