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Article

Iron binding activity is essential for the function of IscA in iron-sulphur cluster biogenesis.

Dalton transactions (Cambridge, England : 2003) - 7 Mar 2013

Landry Aaron P, Cheng Zishuo, Ding Huangen

Abstract excerpt

Iron-sulphur cluster biogenesis requires coordinated delivery of iron and sulphur to scaffold proteins, followed by transfer of the assembled clusters from scaffold proteins to target proteins. This complex process is accomplished by a group of dedicated iron-sulphur cluster assembly proteins that are conserved from bacteria to humans. While sulphur in iron-sulphur clusters is provided by L-cysteine via cysteine...

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PMID: 23258274
DOI: 10.1039/c2dt32000b
PMCID: PMC3569480

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