Article
Distinguishing mouse strains by proteomic analysis of pelage hair.
The Journal of investigative dermatology - 1 Sept 2009
Rice Robert H, Rocke David M, Tsai Hua-Sheng, Silva Kathleen A, Lee Young Jin, Sundberg John P
Abstract excerpt
AKR/J mice display a hair interior defect (hid) phenotype for which the molecular basis is unknown. To investigate the application of hair-shaft proteomics to the study of such diseases, pelage from AKR/J and two other mouse strains without this defect was analyzed by shotgun proteomics. The results permitted the identification of 111 proteins from tryptic digests of total hair from AKR/J-hid/hid mice, which were...
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