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Article

Docetaxel-resistance in prostate cancer: evaluating associated phenotypic changes and potential for resistance transfer via exosomes.

PloS one - 1 Jan 2012

Corcoran Claire, Rani Sweta, O'Brien Keith, O'Neill Amanda, Prencipe Maria, Sheikh Rizwan, Webb Glenn, McDermott Ray, Watson William, Crown John, O'Driscoll Lorraine

Abstract excerpt

BACKGROUND: Hormone-refractory prostate cancer remains hindered by inevitable progression of resistance to first-line treatment with docetaxel. Recent studies suggest that phenotypic changes associated with cancer may be transferred from cell-to-cell via microvesicles/exosomes. Here we aimed to investigate phenotypic changes associated with docetaxel-resistance in order to help determine the complexity of this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23251413
DOI: 10.1371/journal.pone.0050999
PMCID: PMC3519481

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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