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Article

Association of mitochondrial DNA polymerase γ gene POLG1 polymorphisms with parkinsonism in Chinese populations.

PloS one - 1 Jan 2012

Gui Ya-xing, Xu Zhong-ping, Lv Wen, Liu Hong-mei, Zhao Jin-jia, Hu Xing-yue

Abstract excerpt

BACKGROUND: Mitochondrial DNA polymerase gamma (POLG1) mutations were associated with levodopa-responsive Parkinsonism. POLG1 gene contains a number of common nonsynonymous SNPs and intronic regulatory SNPs which may have functional consequences. It is of great interest to discover polymorphisms variants associated with Parkinson's disease (PD), both in isolation and in combination with specific SNPs. MATERIALS...

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Identifiers

PMID: 23251356
DOI: 10.1371/journal.pone.0050086
PMCID: PMC3519471

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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