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Article

POLG1 polyglutamine tract variants associated with Parkinson's disease.

Neuroscience letters - 14 Jun 2010

Eerola Johanna, Luoma Petri T, Peuralinna Terhi, Scholz Sonja, Paisan-Ruiz Coro, Suomalainen Anu, Singleton Andrew B, Tienari Pentti J

Abstract excerpt

A possible role of allelic variation of the mitochondrial DNA polymerase gamma (POLG1) gene in Parkinson's disease (PD) has been suggested. First, POLG1 missense mutations have been found in patients with familial parkinsonism and mitochondrial myopathy. Second, increased frequency of rare alleles of the POLG1 CAG-repeat (poly-Q) has been found in Finnish idiopathic apparently sporadic PD patients, but...

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Identifiers

PMID: 20399836
DOI: 10.1016/j.neulet.2010.04.021
PMCID: PMC2905783

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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