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Article

Variations of mitochondrial DNA polymerase γ in patients with Parkinson's disease.

Journal of neurology - 1 Dec 2013

Ylönen S, Ylikotila P, Siitonen A, Finnilä S, Autere J, Majamaa K

Abstract excerpt

Parkinson's disease is associated with mitochondrial dysfunction. The POLG1 gene encodes DNA-polymerase γ, which is responsible for the replication of mitochondrial DNA. Mutations in POLG1 cause neurodegenerative diseases such as progressive external ophthalmoplegia and Alpers syndrome. In this study, we investigated if mutations in POLG1 had any correlation with Parkinson's disease. Subjects consisted of Finnish...

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Identifiers

PMID: 24122062
DOI: 10.1007/s00415-013-7132-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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