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Article

Detecting rare variants for psychiatric disorders using next generation sequencing: a methods primer.

Current psychiatry reports - 1 Jan 2013

Altmann Andre, Quast Carina, Weber Peter

Abstract excerpt

Recent advances in massively parallel sequencing (MPS) have had an extensive impact on research in medical genomics. In particular, the analysis of rare variants using MPS promises to lead to a better understanding of complex disorders. Nevertheless, for meaningful studies that address the genetic basis for neuropsychiatric disorders, at least hundreds of patient samples have to be analyzed. This undertaking is...

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PMID: 23250814
DOI: 10.1007/s11920-012-0333-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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