Article
Rare variants in TMEM132D in a case-control sample for panic disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Dec 2012
Quast Carina, Altmann Andre, Weber Peter, Arloth Janine, Bader Daniel, Heck Angela, Pfister Hildegard, Müller-Myhsok Bertram, Erhardt Angelika, Binder Elisabeth B
Abstract excerpt
Genome-wide association studies have identified common variants associated with common diseases. Most variants, however, explain only a small proportion of the estimated heritability, suggesting that rare variants might contribute to a larger extent to common diseases than assumed to date. Here, we use next-generation sequencing to test whether such variants contribute to the risk for anxiety disorders by...
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