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Article

Disease-corrected hepatocyte-like cells from familial hypercholesterolemia-induced pluripotent stem cells.

Molecular biotechnology - 1 Jul 2013

Fattahi Faranak, Asgari Samira, Pournasr Behshad, Seifinejad Ali, Totonchi Mehdi, Taei Adeleh, Aghdami Nasser, Salekdeh Ghasem Hosseini, Baharvand Hossein

Abstract excerpt

The generation of human induced pluripotent stem cells (hiPSCs) from an individual patient provides a unique tool for disease modeling, drug discovery, and cell replacement therapies. Patient-specific pluripotent stem cells can be expanded in vitro and are thus suitable for genetic manipulations. To date, several genetic liver disorders have been modeled using patient-specific hiPSCs. Here, we present the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23247991
DOI: 10.1007/s12033-012-9635-3

Genes

LDLR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Disease-corrected hepatocyte-like cells from familial hypercholesterolemia-induced pluripotent stem cells.PMID 23247991Read ↗

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