Article
Profound week 4 interferon responsiveness is mandatory for hepatitis C genotype 1 patients with unfavorable IL-28B genotype.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Apr 2013
Huang Chung-Feng, Yu Ming-Lung, Kao Jia-Horng, Tseng Tai-Chung, Yeh Ming-Lun, Huang Jee-Fu, Dai Chia-Yen, Lin Zu-Yau, Chen Shinn-Cherng, Wang Liang-Yen, Juo Suh-Hang Hank, Chuang Wan-Long, Liu Chen-Hua
Abstract excerpt
BACKGROUND: Viral kinetics and host interleukin 28B (IL-28B) genotype determine treatment outcome in hepatitis C virus genotype 1 (HCV-1) infection. OBJECTIVES: We aimed to explore the interplay between interferon responsiveness at treatment week 4 and IL28B genotype in the achievement of a susta...
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